投稿咨詢
The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.
Some specific areas that are appropriate include the following:
* Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools.
* Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication.
*Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds.
* Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition.
*Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge.
* Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules.
* Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs.
* Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.
《Journal Of Medicinal Chemistry》是一本由AMER CHEMICAL SOC出版商出版的專業醫學期刊，該刊創刊于1963年，刊期Semimonthly，該刊已被國際權威數據庫SCIE、SCI收錄。在中科院最新升級版分區表中，該刊分區信息為大類學科：醫學 2區，小類學科：藥物化學 1區；在JCR（Journal Citation Reports）分區等級為Q1。該刊發文范圍涵蓋藥物化學等領域，旨在及時、準確、全面地報道國內外藥物化學工作者在該領域取得的最新研究成果、工作進展及學術動態、技術革新等，促進學術交流，鼓勵學術創新。2021年影響因子為8.039，平均審稿速度約2.1個月。
| 大類學科 | 分區 | 小類學科 | 分區 | Top期刊 | 綜述期刊 |
| 醫學 | 1區 | CHEMISTRY, MEDICINAL 藥物化學 | 1區 | 是 | 否 |
| JCR分區等級 | JCR所屬學科 | 分區 | 影響因子 |
| Q1 | CHEMISTRY, MEDICINAL | Q1 | 8.039 |
| 影響因子 | h-index | Gold OA文章占比 | 研究類文章占比 | OA開放訪問 | 平均審稿速度 |
| 8.039 | 240 | 12.68% | 99.81% | 未開放 | 約2.1個月 |
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